EBV Target gene Detail Information

> LINC00486 Gene Search Result

Gene Information

Gene Name	LINC00486
Gene ID	285045
Transcripts	ENSG00000230876
Virus	EBV
Gene Type	ncRNA
HPA Location Info
HGNC ID	HGNC:42946
lncRNASNP2 ID	NONHSAG027432.2

Target gene [LINC00486] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000006	chr2	2676	2658	487	5821	View
3000050	chr2	273	234	35	542	View
3300137	chr2	11	92	74	177	View
3300138	chr2	9	92	73	174	View
3300139	chr2	7	76	64	147	View
3300140	chr2	11	94	74	179	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of LINC00486 expression and immune infiltrating cell level correlation result in EBV+ samples
LINC00486 expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of LINC00486 expression and immune infiltrating cell level correlation result in EBV+ samples
LINC00486 expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of LINC00486 expression and immune infiltrating cell level correlation result in EBV+ samples
LINC00486 expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of LINC00486 expression and immune infiltrating cell level correlation result in EBV+ samples
LINC00486 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).