HPV Target gene Detail Information

> LINC00251 Gene Search Result


Gene Information
Gene Name LINC00251
Gene ID 552859
Gene Full Name long intergenic non-protein coding RNA 251
Gene Alias C8orf25; NCRNA00251
Transcripts ENSG00000280725
Virus HPV
Gene Type ncRNA
HPA Location Info
HGNC ID HGNC:31950
VEGA ID OTTHUMG00000189557
lncRNASNP2 ID NONHSAG050394.2
PharmGKB ID PA165585763
Target gene [LINC00251] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403580 chr8 2 1 3 View
5404615 chr8 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of LINC00251 expression and immune infiltrating cell level correlation result in HPV+ samples
LINC00251 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of LINC00251 expression and immune infiltrating cell level correlation result in HPV+ samples
LINC00251 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of LINC00251 expression and immune infiltrating cell level correlation result in HPV+ samples
LINC00251 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of LINC00251 expression and immune infiltrating cell level correlation result in HPV+ samples
LINC00251 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).