HTLV1 Target gene Detail Information

> LIN7C Gene Search Result

Gene Information

Gene Name	LIN7C
Gene ID	55327
Gene Full Name	lin-7 homolog C, crumbs cell polarity complex component
Gene Alias	MALS3; VELI3; LIN-7C; MALS-3; LIN-7-C
Transcripts	ENSG00000148943
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NUP9
HGNC ID	HGNC:17789
VEGA ID	OTTHUMG00000166193
OMIM ID	612332
String ID	9606.ENSP00000278193
PharmGKB ID	PA134891786

Target gene [LIN7C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6025589	chr11	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of LIN7C expression and immune infiltrating cell level correlation result in HTLV1+ samples
LIN7C expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of LIN7C expression and immune infiltrating cell level correlation result in HTLV1+ samples
LIN7C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).