HBV Target gene Detail Information

> LIN52 Gene Search Result

Gene Information

Gene Name	LIN52
Gene ID	91750
Gene Full Name	lin-52 DREAM MuvB core complex component
Gene Alias	C14orf46; c14_5549
Transcripts	ENSG00000205659
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q52LA3
HGNC ID	HGNC:19856
VEGA ID	OTTHUMG00000171204
String ID	9606.ENSP00000451812
PharmGKB ID	PA162394039

Target gene [LIN52] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009852	chr14	2	12		14	View
1009853	chr14	2	12		14	View
1013427	chr14	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LIN52 expression and immune infiltrating cell level correlation result in HBV+ samples
LIN52 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).