HPV Target gene Detail Information

> LHX5 Gene Search Result

Gene Information

Gene Name	LHX5
Gene ID	64211
Gene Full Name	LIM homeobox 5
Transcripts	ENSG00000089116
Virus	HPV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9H2C1
HGNC ID	HGNC:14216
VEGA ID	OTTHUMG00000169552
OMIM ID	605992
String ID	9606.ENSP00000261731
PharmGKB ID	PA30367

Target gene [LHX5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5400351	chr12	45	8	5	58	View
5400352	chr12	25	7	38	70	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of LHX5 expression and immune infiltrating cell level correlation result in HPV+ samples
LHX5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).