HIV Target gene Detail Information

> LDLRAD4 Gene Search Result

Gene Information

Gene Name	LDLRAD4
Gene ID	753
Gene Full Name	low density lipoprotein receptor class A domain containing 4
Gene Alias	C18orf1
Transcripts	ENSG00000168675
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O15165
HGNC ID	HGNC:1224
VEGA ID	OTTHUMG00000181925
OMIM ID	606571
String ID	9606.ENSP00000352420
PharmGKB ID	PA25593

Target gene [LDLRAD4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004214	chr18	17	25	7	49	View
4009179	chr18	7	4	1	12	View
4012265	chr18		5		5	View
4013315	chr18	4			4	View
4013316	chr18	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LDLRAD4 expression and immune infiltrating cell level correlation result in HIV+ samples
LDLRAD4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).