HIV Target gene Detail Information

> LDB2 Gene Search Result

Gene Information

Gene Name	LDB2
Gene ID	9079
Gene Full Name	LIM domain binding 2
Gene Alias	LDB1; CLIM1; LDB-2
Transcripts	ENSG00000169744
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O43679
HGNC ID	HGNC:6533
VEGA ID	OTTHUMG00000048212
OMIM ID	603450
String ID	9606.ENSP00000306772
PharmGKB ID	PA30317

Target gene [LDB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005846	chr3	6	4	19	29	View
4013209	chr4	1		3	4	View
4015677	chr4	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LDB2 expression and immune infiltrating cell level correlation result in HIV+ samples
LDB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of LDB2 expression and immune infiltrating cell level correlation result in HIV+ samples
LDB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).