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HBV Target gene Detail Information

> LCN12 Gene Search Result


Gene Information
Gene Name LCN12
Gene ID 286256
Gene Full Name lipocalin 12
Transcripts ENSG00000184925
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID Q6JVE5
HGNC ID HGNC:28733
VEGA ID OTTHUMG00000020968
OMIM ID 612905
String ID 9606.ENSP00000360696
PharmGKB ID PA134959347
Target gene [LCN12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015962 chr9 1 1 2 View
1017281 chr9 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of LCN12 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
LCN12 expression: Low -> High
Lollipop of LCN12 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of LCN12 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of LCN12 expression and immune infiltrating cell level correlation result in HBV+ samples
LCN12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).