HIV Target gene Detail Information

> LATS1 Gene Search Result

Gene Information

Gene Name	LATS1
Gene ID	9113
Gene Full Name	large tumor suppressor kinase 1
Gene Alias	wts; WARTS
Transcripts	ENSG00000131023
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O95835
HGNC ID	HGNC:6514
VEGA ID	OTTHUMG00000016437
OMIM ID	603473
String ID	9606.ENSP00000437550
Drugbank ID	BE0009409
PharmGKB ID	PA30301

Target gene [LATS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007153	chr6	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LATS1 expression and immune infiltrating cell level correlation result in HIV+ samples
LATS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).