HIV Target gene Detail Information

> LAS1L Gene Search Result

Gene Information

Gene Name	LAS1L
Gene ID	81887
Gene Full Name	LAS1 like, ribosome biogenesis factor
Gene Alias	WTS; Las1-like; dJ475B7.2
Transcripts	ENSG00000001497
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Centriolar satellite;Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9Y4W2
HGNC ID	HGNC:25726
VEGA ID	OTTHUMG00000021720
OMIM ID	300964
String ID	9606.ENSP00000363944
PharmGKB ID	PA128394732

Target gene [LAS1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015486	chrX		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LAS1L expression and immune infiltrating cell level correlation result in HIV+ samples
LAS1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of LAS1L expression and immune infiltrating cell level correlation result in HIV+ samples
LAS1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).