EBV Target gene Detail Information

> LARGE1 Gene Search Result

Gene Information

Gene Name	LARGE1
Gene ID	9215
Gene Full Name	LARGE xylosyl- and glucuronyltransferase 1
Gene Alias	LARGE; MDC1D; MDDGA6; MDDGB6
Transcripts	ENSG00000133424
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O95461
HGNC ID	HGNC:6511
OMIM ID	603590
PharmGKB ID	PA30296

Target gene [LARGE1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000579	chr22	1	8	1	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of LARGE1 expression and immune infiltrating cell level correlation result in EBV+ samples
LARGE1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).