HBV Target gene Detail Information

> LAMB3 Gene Search Result

Gene Information

Gene Name	LAMB3
Gene ID	3914
Gene Full Name	laminin subunit beta 3
Gene Alias	AI1A; LAM5; LAMNB1; BM600-125KDA
Transcripts	ENSG00000196878
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q13751
HGNC ID	HGNC:6490
VEGA ID	OTTHUMG00000036360
OMIM ID	150310
String ID	9606.ENSP00000375778
PharmGKB ID	PA30278

Target gene [LAMB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003315	chr1	26	78	41	145	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LAMB3 expression and immune infiltrating cell level correlation result in HBV+ samples
LAMB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).