HIV Target gene Detail Information

> LAMB1 Gene Search Result


Gene Information
Gene Name LAMB1
Gene ID 3912
Gene Full Name laminin subunit beta 1
Gene Alias CLM; LIS5
Transcripts ENSG00000091136
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P07942
HGNC ID HGNC:6486
VEGA ID OTTHUMG00000149966
OMIM ID 150240
String ID 9606.ENSP00000222399
Drugbank ID BE0002106
PharmGKB ID PA30275
Target gene [LAMB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4012416 chr7 1 1 3 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of LAMB1 expression and immune infiltrating cell level correlation result in HIV+ samples
LAMB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).