HBV Target gene Detail Information

> LAMA5 Gene Search Result

Gene Information

Gene Name	LAMA5
Gene ID	3911
Gene Full Name	laminin subunit alpha 5
Transcripts	ENSG00000130702
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	O15230
HGNC ID	HGNC:6485
VEGA ID	OTTHUMG00000032908
OMIM ID	601033
String ID	9606.ENSP00000252999
Drugbank ID	BE0002103
PharmGKB ID	PA30274

Target gene [LAMA5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007275	chr20	27	1		28	View
1009497	chr20	15			15	View
1403146	chr20	27	1		28	View
1403147	chr20	15			15	View
1404669	chr20	37	112	43	192	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LAMA5 expression and immune infiltrating cell level correlation result in HBV+ samples
LAMA5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).