HBV Target gene Detail Information

> LAMA1 Gene Search Result


Gene Information
Gene Name LAMA1
Gene ID 284217
Gene Full Name laminin subunit alpha 1
Gene Alias LAMA; PTBHS; S-LAM-alpha
Transcripts ENSG00000101680
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P25391
HGNC ID HGNC:6481
VEGA ID OTTHUMG00000133478
OMIM ID 150320
String ID 9606.ENSP00000374309
Drugbank ID BE0002108
PharmGKB ID PA30270
Target gene [LAMA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008133 chr18 16 5 1 22 View
1009830 chr18 11 2 1 14 View
1010119 chr18 11 2 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of LAMA1 expression and immune infiltrating cell level correlation result in HBV+ samples
LAMA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).