HBV Target gene Detail Information

> L3MBTL4 Gene Search Result

Gene Information

Gene Name	L3MBTL4
Gene ID	91133
Gene Full Name	L3MBTL4, histone methyl-lysine binding protein
Gene Alias	HsT1031
Transcripts	ENSG00000154655
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q8NA19
HGNC ID	HGNC:26677
VEGA ID	OTTHUMG00000178980
OMIM ID	617135
String ID	9606.ENSP00000382976
PharmGKB ID	PA134935795

Target gene [L3MBTL4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003007	chr18	39	129	9	177	View
1007917	chr18	2	21		23	View
1018939	chr18				0	View
1401512	chr18	2	21		23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of L3MBTL4 expression and immune infiltrating cell level correlation result in HBV+ samples
L3MBTL4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).