HIV Target gene Detail Information

> L3MBTL2 Gene Search Result


Gene Information
Gene Name L3MBTL2
Gene ID 83746
Gene Full Name L3MBTL2, polycomb repressive complex 1 subunit
Gene Alias L3MBT; H-l(3)mbt-l
Transcripts ENSG00000100395
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q969R5
HGNC ID HGNC:18594
VEGA ID OTTHUMG00000150942
OMIM ID 611865
String ID 9606.ENSP00000216237
PharmGKB ID PA38356
Target gene [L3MBTL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4007374 chr22 19 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of L3MBTL2 expression and immune infiltrating cell level correlation result in HIV+ samples
L3MBTL2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of L3MBTL2 expression and immune infiltrating cell level correlation result in HIV+ samples
L3MBTL2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).