HTLV1 Target gene Detail Information

> KY Gene Search Result

Gene Information

Gene Name	KY
Gene ID	339855
Gene Full Name	kyphoscoliosis peptidase
Gene Alias	MFM7
Transcripts	ENSG00000174611
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8NBH2
HGNC ID	HGNC:26576
VEGA ID	OTTHUMG00000159788
OMIM ID	605739
String ID	9606.ENSP00000397598
PharmGKB ID	PA134878738

Target gene [KY] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6012793	chr3	19	2		21	View
6026614	chrY	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KY expression and immune infiltrating cell level correlation result in HTLV1+ samples
KY expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of KY expression and immune infiltrating cell level correlation result in HTLV1+ samples
KY expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of KY expression and immune infiltrating cell level correlation result in HTLV1+ samples
KY expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).