HIV Target gene Detail Information

> KNSTRN Gene Search Result

Gene Information

Gene Name	KNSTRN
Gene ID	90417
Gene Full Name	kinetochore localized astrin (SPAG5) binding protein
Gene Alias	SKAP; HSD11; C15orf23; TRAF4AF1
Transcripts	ENSG00000128944
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Mitotic spindle;Plasma membrane;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9Y448
HGNC ID	HGNC:30767
VEGA ID	OTTHUMG00000172454
OMIM ID	614718
String ID	9606.ENSP00000249776
PharmGKB ID	PA134895025

Target gene [KNSTRN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004890	chr15	38			38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KNSTRN expression and immune infiltrating cell level correlation result in HIV+ samples
KNSTRN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).