HIV Target gene Detail Information

> KMT2E Gene Search Result

Gene Information

Gene Name	KMT2E
Gene ID	55904
Gene Full Name	lysine methyltransferase 2E
Gene Alias	MLL5; NKp44L; HDCMC04P
Transcripts	ENSG00000005483
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8IZD2
HGNC ID	HGNC:18541
VEGA ID	OTTHUMG00000157403
OMIM ID	608444
String ID	9606.ENSP00000312379
PharmGKB ID	PA38568

Target gene [KMT2E] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001710	chr7	21	15	102	138	View
4004956	chr7	23	14		37	View
4005023	chr7	16	18	3	37	View
4009096	chr7	10	3		13	View
4009097	chr7	10	3		13	View
4009098	chr7	10	3		13	View
4012609	chr7		5		5	View
4015141	chr7	1			1	View
4100048	chr7	38	8		46	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KMT2E expression and immune infiltrating cell level correlation result in HIV+ samples
KMT2E expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).