Home
Virus
Gene
Disease
Dataset
Download
Help
 
EBV Target gene Detail Information

> KMT2D Gene Search Result


Gene Information
Gene Name KMT2D
Gene ID 8085
Gene Full Name lysine methyltransferase 2D
Gene Alias ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
Transcripts ENSG00000167548
Virus EBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID O14686
HGNC ID HGNC:7133
VEGA ID OTTHUMG00000166524
OMIM ID 602113
String ID 9606.ENSP00000301067
PharmGKB ID PA30846
Target gene [KMT2D] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 30546078 A1289T
BNRF1
R
S
C
 View
2 30546078 S654P
BBLF2/BBLF3
R
S
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of KMT2D expression and immune infiltrating cell level correlation result in EBV+ samples
KMT2D expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of KMT2D expression and immune infiltrating cell level correlation result in EBV+ samples
KMT2D expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of KMT2D expression and immune infiltrating cell level correlation result in EBV+ samples
KMT2D expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of KMT2D expression and immune infiltrating cell level correlation result in EBV+ samples
KMT2D expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of KMT2D expression and immune infiltrating cell level correlation result in EBV+ samples
KMT2D expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).