EBV Target gene Detail Information

> KLHL33 Gene Search Result

Gene Information

Gene Name	KLHL33
Gene ID	123103
Gene Full Name	kelch like family member 33
Transcripts	ENSG00000185271
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	A6NCF5
HGNC ID	HGNC:31952
VEGA ID	OTTHUMG00000170982
String ID	9606.ENSP00000341549
PharmGKB ID	PA162393579

Target gene [KLHL33] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000103	chr14	159	4	11	174	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE45919 (GEO)	Infectious mononucleosis	24	Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO)	Multiple sclerosis	32	Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of KLHL33 expression and immune infiltrating cell level correlation result in EBV+ samples
KLHL33 expression: Low -> High

> Dataset: GSE45919
HeatMap of cell type fractions in all samples	Lollipop of KLHL33 expression and immune infiltrating cell level correlation result in EBV+ samples
KLHL33 expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of KLHL33 expression and immune infiltrating cell level correlation result in EBV+ samples
KLHL33 expression: Low -> High

> Dataset: GSE58240
HeatMap of cell type fractions in all samples	Lollipop of KLHL33 expression and immune infiltrating cell level correlation result in EBV+ samples
KLHL33 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).