HIV Target gene Detail Information

> KLHDC7B Gene Search Result

Gene Information

Gene Name	KLHDC7B
Gene ID	113730
Gene Full Name	kelch domain containing 7B
Transcripts	ENSG00000130487
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96G42
HGNC ID	HGNC:25145
VEGA ID	OTTHUMG00000150250
String ID	9606.ENSP00000379034
PharmGKB ID	PA142671582

Target gene [KLHDC7B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006433	chr22	25			25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KLHDC7B expression and immune infiltrating cell level correlation result in HIV+ samples
KLHDC7B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KLHDC7B expression and immune infiltrating cell level correlation result in HIV+ samples
KLHDC7B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).