EBV Target gene Detail Information

> KIZ Gene Search Result

Gene Information

Gene Name	KIZ
Gene ID	55857
Gene Full Name	kizuna centrosomal protein
Gene Alias	RP69; HT013; Kizuna; PLK1S1; C20orf19; NCRNA00153
Transcripts	ENSG00000088970
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q2M2Z5
HGNC ID	HGNC:15865
VEGA ID	OTTHUMG00000032020
OMIM ID	615757
String ID	9606.ENSP00000479542
PharmGKB ID	PA165392491

Target gene [KIZ] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000130	chr20	14	98	16	128	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of KIZ expression and immune infiltrating cell level correlation result in EBV+ samples
KIZ expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of KIZ expression and immune infiltrating cell level correlation result in EBV+ samples
KIZ expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of KIZ expression and immune infiltrating cell level correlation result in EBV+ samples
KIZ expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).