HIV Target gene Detail Information

> KIF5B Gene Search Result

Gene Information

Gene Name	KIF5B
Gene ID	3799
Gene Full Name	kinesin family member 5B
Gene Alias	KNS; KINH; KNS1; UKHC; HEL-S-61
Transcripts	ENSG00000170759
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P33176
HGNC ID	HGNC:6324
VEGA ID	OTTHUMG00000017913
OMIM ID	602809
String ID	9606.ENSP00000307078
PharmGKB ID	PA30108

Target gene [KIF5B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009514	chr10	6	5		11	View
4013514	chr10	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KIF5B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF5B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KIF5B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF5B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).