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HBV Target gene Detail Information

> KIF5A Gene Search Result


Gene Information
Gene Name KIF5A
Gene ID 3798
Gene Full Name kinesin family member 5A
Gene Alias NKHC; ALS25; MY050; NEIMY; SPG10; D12S1889
Transcripts ENSG00000155980
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Mitotic spindle;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q12840
HGNC ID HGNC:6323
VEGA ID OTTHUMG00000170143
OMIM ID 602821
String ID 9606.ENSP00000408979
PharmGKB ID PA30107
Target gene [KIF5A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1402992 chr12 12 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of KIF5A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
KIF5A expression: Low -> High
Lollipop of KIF5A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of KIF5A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KIF5A expression and immune infiltrating cell level correlation result in HBV+ samples
KIF5A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).