HPV Target gene Detail Information

> KIF4B Gene Search Result

Gene Information

Gene Name	KIF4B
Gene ID	285643
Gene Full Name	kinesin family member 4B
Transcripts	ENSG00000226650
Virus	HPV
Gene Type	protein coding
HPA Location Info	Midbody;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q2VIQ3
HGNC ID	HGNC:6322
VEGA ID	OTTHUMG00000164143
OMIM ID	609184
String ID	9606.ENSP00000387875
PharmGKB ID	PA30106

Target gene [KIF4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5404044	chr5	20	3	1	24	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of KIF4B expression and immune infiltrating cell level correlation result in HPV+ samples
KIF4B expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of KIF4B expression and immune infiltrating cell level correlation result in HPV+ samples
KIF4B expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of KIF4B expression and immune infiltrating cell level correlation result in HPV+ samples
KIF4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).