HIV Target gene Detail Information

> KIF2C Gene Search Result

Gene Information

Gene Name	KIF2C
Gene ID	11004
Gene Full Name	kinesin family member 2C
Gene Alias	MCAK; CT139; KNSL6
Transcripts	ENSG00000142945
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;Nucleoplasm;Midbody;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q99661
HGNC ID	HGNC:6393
VEGA ID	OTTHUMG00000008416
OMIM ID	604538
String ID	9606.ENSP00000361298
Drugbank ID	BE0004622
PharmGKB ID	PA30182

Target gene [KIF2C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001099	chr1	32	171	12	215	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KIF2C expression and immune infiltrating cell level correlation result in HIV+ samples
KIF2C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).