HBV Target gene Detail Information

> KIF26B Gene Search Result


Gene Information
Gene Name KIF26B
Gene ID 55083
Gene Full Name kinesin family member 26B
Transcripts ENSG00000281216
Virus HBV
Gene Type protein coding
HPA Location Info Microtubules;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q2KJY2
HGNC ID HGNC:25484
VEGA ID OTTHUMG00000189639
OMIM ID 614026
String ID 9606.ENSP00000385545
PharmGKB ID PA145148575
Target gene [KIF26B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004490 chr1 39 21 19 79 View
1004506 chr1 39 21 19 79 View
1004682 chr1 19 4 49 72 View
1013175 chr1 1 3 1 5 View
1018168 chr1 0 View
1019528 chr1 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of KIF26B expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
KIF26B expression: Low -> High
Lollipop of KIF26B expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of KIF26B expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KIF26B expression and immune infiltrating cell level correlation result in HBV+ samples
KIF26B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).