HIV Target gene Detail Information

> KIF22 Gene Search Result


Gene Information
Gene Name KIF22
Gene ID 3835
Gene Full Name kinesin family member 22
Gene Alias KID; OBP; KNSL4; OBP-1; OBP-2; SEMDJL2; A-328A3.2
Transcripts ENSG00000079616
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q14807
HGNC ID HGNC:6391
VEGA ID OTTHUMG00000097771
OMIM ID 603213
String ID 9606.ENSP00000160827
PharmGKB ID PA30180
Target gene [KIF22] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004280 chr16 45 1 46 View
4010699 chr16 7 1 8 View
4014959 chr16 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of KIF22 expression and immune infiltrating cell level correlation result in HIV+ samples
KIF22 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of KIF22 expression and immune infiltrating cell level correlation result in HIV+ samples
KIF22 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).