HIV Target gene Detail Information

> KIF22 Gene Search Result

Gene Information

Gene Name	KIF22
Gene ID	3835
Gene Full Name	kinesin family member 22
Gene Alias	KID; OBP; KNSL4; OBP-1; OBP-2; SEMDJL2; A-328A3.2
Transcripts	ENSG00000079616
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q14807
HGNC ID	HGNC:6391
VEGA ID	OTTHUMG00000097771
OMIM ID	603213
String ID	9606.ENSP00000160827
PharmGKB ID	PA30180

Target gene [KIF22] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004280	chr16	45	1		46	View
4010699	chr16	7	1		8	View
4014959	chr16		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KIF22 expression and immune infiltrating cell level correlation result in HIV+ samples
KIF22 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KIF22 expression and immune infiltrating cell level correlation result in HIV+ samples
KIF22 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).