HIV Target gene Detail Information

> KIF21B Gene Search Result

Gene Information

Gene Name	KIF21B
Gene ID	23046
Gene Full Name	kinesin family member 21B
Transcripts	ENSG00000116852
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Mitotic spindle;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O75037
HGNC ID	HGNC:29442
VEGA ID	OTTHUMG00000035787
OMIM ID	608322
String ID	9606.ENSP00000411831
PharmGKB ID	PA134925106

Target gene [KIF21B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000155	chr1	855	5	2	862	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KIF21B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF21B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KIF21B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF21B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).