HIV Target gene Detail Information

> KIF1B Gene Search Result

Gene Information

Gene Name	KIF1B
Gene ID	23095
Gene Full Name	kinesin family member 1B
Gene Alias	KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1
Transcripts	ENSG00000054523
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;Nucleoli fibrillar center;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O60333
HGNC ID	HGNC:16636
VEGA ID	OTTHUMG00000001817
OMIM ID	605995
String ID	9606.ENSP00000263934
PharmGKB ID	PA38176

Target gene [KIF1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000595	chr1	144	39	176	359	View
4003501	chr1	59	1		60	View
4004457	chr1	16	28		44	View
4006729	chr1	23			23	View
4012824	chr1	4			4	View
4013267	chr1	3	1		4	View
4015195	chr1	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KIF1B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF1B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KIF1B expression and immune infiltrating cell level correlation result in HIV+ samples
KIF1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).