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HBV Target gene Detail Information

> KIAA1109 Gene Search Result


Gene Information
Gene Name KIAA1109
Gene ID 84162
Gene Full Name KIAA1109
Gene Alias FSA; Tweek; ALKKUCS
Transcripts ENSG00000138688
Virus HBV
Gene Type protein coding
HPA Location Info Centrosome;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q2LD37
HGNC ID HGNC:26953
VEGA ID OTTHUMG00000150116
OMIM ID 611565
String ID 9606.ENSP00000264501
PharmGKB ID PA142671621
Target gene [KIAA1109] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016736 chr4 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of KIAA1109 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
KIAA1109 expression: Low -> High
Lollipop of KIAA1109 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of KIAA1109 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KIAA1109 expression and immune infiltrating cell level correlation result in HBV+ samples
KIAA1109 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).