HTLV1 Target gene Detail Information

> KDSR Gene Search Result

Gene Information

Gene Name	KDSR
Gene ID	2531
Gene Full Name	3-ketodihydrosphingosine reductase
Gene Alias	DHSR; FVT1; EKVP4; SDR35C1
Transcripts	ENSG00000119537
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q06136
HGNC ID	HGNC:4021
VEGA ID	OTTHUMG00000132792
OMIM ID	136440
String ID	9606.ENSP00000385083
PharmGKB ID	PA162392777

Target gene [KDSR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000269	chr18	2239	126	105	2470	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KDSR expression and immune infiltrating cell level correlation result in HTLV1+ samples
KDSR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).