|
Gene Information
|
Gene Name
|
KDR |
|
Gene ID
|
3791
|
|
Gene Full Name
|
kinase insert domain receptor |
|
Gene Alias
|
FLK1; CD309; VEGFR; VEGFR2 |
|
Transcripts
|
ENSG00000128052
|
|
Virus
|
HBV |
|
Gene Type
|
protein coding |
|
HPA Location Info
|
Plasma membrane; 
|
|
Membrane Info
|
Predicted membrane proteins |
|
HPA Protein Class Info
|
Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins |
|
Uniport_ID
|
P35968
|
|
HGNC ID
|
HGNC:6307
|
|
VEGA ID
|
OTTHUMG00000128734
|
|
OMIM ID
|
191306 |
|
String ID
|
9606.ENSP00000263923
|
|
Drugbank ID
|
BE0000369
|
|
Drug (Cytoscape Annotation)
|
Regorafenib;Sunitinib Malate;Ramucirumab;Lenvatinib Mesylate;Sorafenib Tosylate;Ponatinib Hydrochloride;ErlotinibHydrochloride;Axitinib;Vandetanib;Pazopanib Hydrochloride |
|
PharmGKB ID
|
PA30086
|
|
FDA Approved Drug
|
Lenvatinib;Ponatinib;Ramucirumab;Sorafenib;Pazopanib;Vandetanib;Sunitinib;Regorafenib;Cabozantinib;Midostaurin;Axitinib |
Target gene [KDR] related to VISs 
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1013654 |
chr4 |
3 |
1 |
|
4 |
View |
| 1013892 |
chr4 |
4 |
|
|
4 |
View |
| 1016647 |
chr4 |
1 |
|
|
1 |
View |
Relationship between gene expression and immune infiltrating cell level
| Data ID |
Disease |
Sample number |
Sample type |
|
LIHC (TCGA) |
Liver hepatocellular carcinoma |
424 |
Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18) |
> Dataset: LIHC
|
|
HeatMap of cell type fractions in all samples
|
Lollipop of KDR expression and immune infiltrating cell level correlation result in HBV+ samples
|
KDR expression: Low -> High
|
|
|
|
|
HBV Target gene Detail Information