HBV Target gene Detail Information

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Gene Information

Gene Name	KDR
Gene ID	3791
Gene Full Name	kinase insert domain receptor
Gene Alias	FLK1; CD309; VEGFR; VEGFR2
Transcripts	ENSG00000128052
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins
Uniport_ID	P35968
HGNC ID	HGNC:6307
VEGA ID	OTTHUMG00000128734
OMIM ID	191306
String ID	9606.ENSP00000263923
Drugbank ID	BE0000369
Drug (Cytoscape Annotation)	Regorafenib;Sunitinib Malate;Ramucirumab;Lenvatinib Mesylate;Sorafenib Tosylate;Ponatinib Hydrochloride;ErlotinibHydrochloride;Axitinib;Vandetanib;Pazopanib Hydrochloride
PharmGKB ID	PA30086
FDA Approved Drug	Lenvatinib;Ponatinib;Ramucirumab;Sorafenib;Pazopanib;Vandetanib;Sunitinib;Regorafenib;Cabozantinib;Midostaurin;Axitinib

Target gene [KDR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013654	chr4	3	1		4	View
1013892	chr4	4			4	View
1016647	chr4	1			1	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).