HIV Target gene Detail Information

> KDM6B Gene Search Result

Gene Information

Gene Name	KDM6B
Gene ID	23135
Gene Full Name	lysine demethylase 6B
Gene Alias	JMJD3
Transcripts	ENSG00000132510
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O15054
HGNC ID	HGNC:29012
VEGA ID	OTTHUMG00000178021
OMIM ID	611577
String ID	9606.ENSP00000254846
PharmGKB ID	PA165431973

Target gene [KDM6B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001840	chr17	121	6		127	View
4003952	chr17	51	1		52	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KDM6B expression and immune infiltrating cell level correlation result in HIV+ samples
KDM6B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KDM6B expression and immune infiltrating cell level correlation result in HIV+ samples
KDM6B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).