HTLV1 Target gene Detail Information

> KDM5D Gene Search Result

Gene Information

Gene Name	KDM5D
Gene ID	8284
Gene Full Name	lysine demethylase 5D
Gene Alias	HY; HYA; SMCY; JARID1D
Transcripts	ENSG00000012817
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9BY66
HGNC ID	HGNC:11115
VEGA ID	OTTHUMG00000036508
OMIM ID	426000
Drugbank ID	BE0002215
PharmGKB ID	PA35965

Target gene [KDM5D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6022983	chrY	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KDM5D expression and immune infiltrating cell level correlation result in HTLV1+ samples
KDM5D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).