HTLV1 Target gene Detail Information

> KDM4D Gene Search Result

Gene Information

Gene Name	KDM4D
Gene ID	55693
Gene Full Name	lysine demethylase 4D
Gene Alias	JMJD2D
Transcripts	ENSG00000186280
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6B0I6
HGNC ID	HGNC:25498
VEGA ID	OTTHUMG00000167838
OMIM ID	609766
String ID	9606.ENSP00000334181
PharmGKB ID	PA164721552

Target gene [KDM4D] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6020083	chr11	6		1	7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KDM4D expression and immune infiltrating cell level correlation result in HTLV1+ samples
KDM4D expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).