HBV Target gene Detail Information

> KDM4B Gene Search Result

Gene Information

Gene Name	KDM4B
Gene ID	23030
Gene Full Name	lysine demethylase 4B
Gene Alias	JMJD2B; TDRD14B
Transcripts	ENSG00000127663
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O94953
HGNC ID	HGNC:29136
VEGA ID	OTTHUMG00000180281
OMIM ID	609765
String ID	9606.ENSP00000159111
PharmGKB ID	PA164721452

Target gene [KDM4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001579	chr19	40	489	75	604	View
1004134	chr19	34	35	24	93	View
1005797	chr19	36	10	3	49	View
1404665	chr19	39	4	19	62	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KDM4B expression and immune infiltrating cell level correlation result in HBV+ samples
KDM4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).