HIV Target gene Detail Information

> KDM4A Gene Search Result

Gene Information

Gene Name	KDM4A
Gene ID	9682
Gene Full Name	lysine demethylase 4A
Gene Alias	JMJD2; JHDM3A; JMJD2A; TDRD14A
Transcripts	ENSG00000066135
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75164
HGNC ID	HGNC:22978
VEGA ID	OTTHUMG00000007560
OMIM ID	609764
String ID	9606.ENSP00000361473
PharmGKB ID	PA164721403

Target gene [KDM4A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001615	chr1	94	2	50	146	View
4008576	chr1	5	8	1	14	View
4300085	chr1	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KDM4A expression and immune infiltrating cell level correlation result in HIV+ samples
KDM4A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).