HIV Target gene Detail Information

> KDM3B Gene Search Result

Gene Information

Gene Name	KDM3B
Gene ID	51780
Gene Full Name	lysine demethylase 3B
Gene Alias	5qNCA; NET22; C5orf7; JMJD1B
Transcripts	ENSG00000120733
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q7LBC6
HGNC ID	HGNC:1337
VEGA ID	OTTHUMG00000163469
OMIM ID	609373
String ID	9606.ENSP00000326563
PharmGKB ID	PA25918

Target gene [KDM3B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011267	chr5	2	5		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of KDM3B expression and immune infiltrating cell level correlation result in HIV+ samples
KDM3B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of KDM3B expression and immune infiltrating cell level correlation result in HIV+ samples
KDM3B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).