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HBV Target gene Detail Information

> KCNT2 Gene Search Result


Gene Information
Gene Name KCNT2
Gene ID 343450
Gene Full Name potassium sodium-activated channel subfamily T member 2
Gene Alias SLICK; EIEE57; KCa4.2; SLO2.1
Transcripts ENSG00000162687
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q6UVM3
HGNC ID HGNC:18866
VEGA ID OTTHUMG00000035611
OMIM ID 610044
String ID 9606.ENSP00000294725
PharmGKB ID PA38726
Target gene [KCNT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001495 chr1 294 137 273 704 View
1001734 chr1 140 145 227 512 View
1003104 chr1 11 47 108 166 View
1003105 chr1 11 47 108 166 View
1004667 chr1 70 3 73 View
1004750 chr1 48 12 10 70 View
1006199 chr1 9 33 42 View
1007560 chr1 16 10 26 View
1007598 chr1 18 3 5 26 View
1008578 chr1 17 2 1 20 View
1009177 chr1 17 17 View
1009178 chr1 17 17 View
1009447 chr1 12 4 16 View
1009615 chr1 11 4 15 View
1009870 chr1 10 4 14 View
1010835 chr1 6 4 1 11 View
1015571 chr1 2 2 View
1016132 chr1 1 1 2 View
1016520 chr1 1 1 View
1016521 chr1 1 1 View
1016758 chr1 1 1 View
1017356 chr1 1 1 View
1017357 chr1 1 1 View
1018091 chr1 0 View
1018092 chr1 0 View
1018550 chr1 0 View
1404343 chr1 3 5 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNT2 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNT2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).