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HBV Target gene Detail Information

> KCNS3 Gene Search Result


Gene Information
Gene Name KCNS3
Gene ID 3790
Gene Full Name potassium voltage-gated channel modifier subfamily S member 3
Gene Alias KV9.3
Transcripts ENSG00000170745
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Golgi apparatus;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q9BQ31
HGNC ID HGNC:6302
VEGA ID OTTHUMG00000044150
OMIM ID 603888
String ID 9606.ENSP00000385968
Drugbank ID BE0010047; BE0009847
PharmGKB ID PA30080
Target gene [KCNS3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001661 chr2 28 284 229 541 View
1005368 chr2 11 29 16 56 View
1011177 chr2 3 5 2 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNS3 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNS3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).