HBV Target gene Detail Information

> KCNQ5 Gene Search Result

Gene Information

Gene Name	KCNQ5
Gene ID	56479
Gene Full Name	potassium voltage-gated channel subfamily Q member 5
Gene Alias	Kv7.5; MRD46
Transcripts	ENSG00000185760
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q9NR82
HGNC ID	HGNC:6299
VEGA ID	OTTHUMG00000015020
OMIM ID	607357
String ID	9606.ENSP00000345055
Drugbank ID	BE0002400; BE0009847
PharmGKB ID	PA30077

Target gene [KCNQ5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013657	chr6	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNQ5 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNQ5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).