HBV Target gene Detail Information

> KCNQ4 Gene Search Result

Gene Information

Gene Name	KCNQ4
Gene ID	9132
Gene Full Name	potassium voltage-gated channel subfamily Q member 4
Gene Alias	DFNA2; KV7.4; DFNA2A
Transcripts	ENSG00000117013
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	P56696
HGNC ID	HGNC:6298
VEGA ID	OTTHUMG00000007730
OMIM ID	603537
String ID	9606.ENSP00000262916
Drugbank ID	BE0002399; BE0009847
PharmGKB ID	PA30076

Target gene [KCNQ4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012897	chr1	4	1	1	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNQ4 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNQ4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).