HBV Target gene Detail Information

> KCNQ3 Gene Search Result

Gene Information

Gene Name	KCNQ3
Gene ID	3786
Gene Full Name	potassium voltage-gated channel subfamily Q member 3
Gene Alias	EBN2; BFNC2; KV7.3
Transcripts	ENSG00000184156
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	O43525
HGNC ID	HGNC:6297
VEGA ID	OTTHUMG00000137472
OMIM ID	602232
String ID	9606.ENSP00000373648
Drugbank ID	BE0002398; BE0009847
PharmGKB ID	PA30075

Target gene [KCNQ3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015482	chr8	1	1		2	View
1019763	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNQ3 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNQ3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).