HTLV1 Target gene Detail Information

> KCNQ1OT1 Gene Search Result

Gene Information

Gene Name	KCNQ1OT1
Gene ID	10984
Gene Alias	LIT1; Kncq1; KvDMR1; KCNQ10T1; KCNQ1-AS2; KvLQT1-AS; NCRNA00012
Transcripts	ENSG00000269821
Virus	HTLV1
Gene Type	ncRNA
HPA Location Info
HGNC ID	HGNC:6295
VEGA ID	OTTHUMG00000171022
OMIM ID	604115
lncRNASNP2 ID	NONHSAG007431.2
PharmGKB ID	PA30073

Target gene [KCNQ1OT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003725	chr11	124	17	3	144	View
6004034	chr11	109	17	5	131	View
6015276	chr11	13	1		14	View
6032070	chr11				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of KCNQ1OT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
KCNQ1OT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).