HBV Target gene Detail Information

> KCNN3 Gene Search Result

Gene Information

Gene Name	KCNN3
Gene ID	3782
Gene Full Name	potassium calcium-activated channel subfamily N member 3
Gene Alias	SK3; hSK3; SKCA3; KCa2.3
Transcripts	ENSG00000143603
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q9UGI6
HGNC ID	HGNC:6292
VEGA ID	OTTHUMG00000037260
OMIM ID	602983
String ID	9606.ENSP00000481848
Drugbank ID	BE0004427; BE0004906
PharmGKB ID	PA30072

Target gene [KCNN3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010924	chr1	10			10	View
1013468	chr1		5		5	View
1400510	chr1	15		7	22	View
1402879	chr1	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of KCNN3 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNN3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).