HBV Target gene Detail Information

> KCNN2 Gene Search Result


Gene Information
Gene Name KCNN2
Gene ID 3781
Gene Full Name potassium calcium-activated channel subfamily N member 2
Gene Alias SK2; hSK2; SKCA2; KCa2.2; SKCa 2
Transcripts ENSG00000080709
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q9H2S1
HGNC ID HGNC:6291
VEGA ID OTTHUMG00000128836
OMIM ID 605879
String ID 9606.ENSP00000427120
Drugbank ID BE0004426; BE0004906
PharmGKB ID PA30071
Target gene [KCNN2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1013374 chr5 3 2 5 View
1014816 chr5 3 3 View
1016798 chr5 1 1 View
1018924 chr5 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of KCNN2 expression and immune infiltrating cell level correlation result in HBV+ samples
KCNN2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).